Teenage brain drain
Teenagers struck by early-onset psychosis quickly exhibit brain volume decreases over two years, according to a new study in theContinue Reading
Category: Schizophrenia Research Forum
Omens of psychosis?
An overactive dopamine system in the brain precedes the onset of psychosis, according to a recent study in American JournalContinue Reading
Spontaneous mutations linked to bipolar disorder
Bipolar disorder has joined the ranks of brain disorders associated with mutations called copy number variations (CNVs) — specifically spontaneously-occurringContinue Reading
Uninherited genetic glitches in schizophrenia
People with schizophrenia carry a higher number of copy number variations (CNVs) — gains and losses of DNA segments —Continue Reading
DISC1: Of mice, men, and…amoebas?
Recent findings in humans, mice, zebrafish, and even the humble amoeba offer new insights, confirm older ones, and in someContinue Reading
Antipsychotic balancing act?
A new study in Cell proposes that the therapeutic effects of both atypical antipsychotic drugs and the newer glutamate candidates dependContinue Reading
Cortical thinning in schizophrenia: interpret with care
Only a few millimeters thick, the cortical layer contains the neurons and connections that comprise much of the brain’s workforce,Continue Reading
Filling in the function gap
Two new studies published in Neuron start to sort out how changes to DISC1, schizophrenia’s most famous gene, alter brainContinue Reading
Parsing dysbindin
There’s something for everyone’s pet hypothesis of schizophrenia in two recent studies of dysbindin-1, a protein involved in shuttling proteinsContinue Reading
The life and times of the human brain transcriptome
A dynamic view of transcription in the human brain has been revealed in two papers published in Nature. Both studiesContinue Reading
WCPG 2011 — Enter the endophenotype
The last day of the meeting featured endophenotypes — characteristics like impulsivity that lie between genes and full-blown disease —Continue Reading
WCPG 2011 — Deciphering dysbindin
A session devoted to dysbindin, a protein encoded by a gene linked to schizophrenia, showed more than a few biologistsContinue Reading
Michele Solis 