SIRS 2012 — Immunology takes center stage
The immune system and its contribution to schizophrenia risk was featured in many talks, suggesting it has moved beyond itsContinue Reading
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SIRS 2012 — The pile of schizophrenia genetics puzzle pieces grows
More than 1,600 researchers and clinicians gathered in a Florence from 14-18 April 2012 to discuss new schizophrenia research atContinue Reading
Personality circuits
We typically reveal our personalities through our behavior, but a new study suggests it might be apparent even when weContinue Reading
Stress pathway dysregulated in autism models
Two studies report abnormalities in the system that mediates the body’s response to stress in mouse models of Angelman syndrome andContinue Reading
Autism exomes revealed
Spontaneously occurring, protein-altering mutations likely contribute to some cases of autism, according to a trio of the largest-to-date exome sequencingContinue Reading
Making sense of a maze
Trillions of synapses in the human brain connect neurons near and far, with information traversing different paths within this mazeContinue Reading
What (engineered) memories are made of
Sometimes the best way to understand how something works is to try to build it — and researchers have takenContinue Reading
Stress leaves its mark on the brain
Stressful experiences turn down signaling of the chemical messenger glutamate in the rat brain, according to a recent study inContinue Reading
Target potassium channels for schizophrenia?
Adding extra dopamine receptors to the mouse striatum—a manipulation that models the overactive dopamine signaling hypothesized in schizophrenia—can substantially remodelContinue Reading
DNA damage
Disorder-specific patterns of DNA damage in neurons mark the brain in schizophrenia and bipolar disorder, according to a recent studyContinue Reading
Collective commons
Common variants capture at least 23 percent of liability for schizophrenia, according to a study published in Nature Genetics. TheContinue Reading
Intracellular gridlock
Proteins encoded by DISC1, a gene suspected in schizophrenia, can clump together and slow transport of essential components inside aContinue Reading
Michele Solis 