Stress leaves its mark on the brain
Stressful experiences turn down signaling of the chemical messenger glutamate in the rat brain, according to a recent study inContinue Reading
Tag: glutamate hypothesis
Parsing dysbindin
There’s something for everyone’s pet hypothesis of schizophrenia in two recent studies of dysbindin-1, a protein involved in shuttling proteinsContinue Reading
Kynurenine crossroads
An enzyme that degrades kynurenine — a chemical by-product of tryptophan — can promote either neuroprotective or neurotoxic effects inContinue Reading
Ketamine as antidepressant
A single dose of ketamine can relieve depression in as little as two hours, but finding out how it worksContinue Reading
Dark horses of anxiety
Two recent studies turn up new clues about anxiety in obscure places. In the space between neurons, an enzyme calledContinue Reading
Advancing drug discovery for schizophrenia
Over 200 researchers gathered at the lofty, fortieth floor location of the New York Academy of Sciences on 10-11 March 2011Continue Reading
Meet Norbin
Researchers have identified the protein Norbin as a behind the scenes booster of metabotropic glutamate receptors. This suggests a potentialContinue Reading
Getting specific with a mouse model of schizophrenia
Removing a subset of NMDA receptors in mice early in development can disrupt neural circuits and behavior in ways thatContinue Reading
Michele Solis 