Experimental cancer drugs called PAK inhibitors can promote connections between neurons in a genetic mouse model of psychiatric disorders, reports a study in the Proceedings of the National Academy of Sciences. The researchers developed compounds that inhibit p21-activated kinases (PAKs), and these protected or restored dendritic spines — the knobby recipients of inputs from other neurons — in the mice, and rescued deficits similar to those seen in schizophrenia.
Read this story at Schizophrenia Research Forum.
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Experimental cancer drugs called PAK inhibitors can promote connections between neurons in a genetic mouse model of psychiatric disorders, reports a study in the Proceedings of the National Academy of Sciences. The researchers developed compounds that inhibit p21-activated kinases (PAKs), and these protected or restored dendritic spines — the knobby recipients of inputs from other neurons — in the mice, and rescued deficits similar to those seen in schizophrenia.
Read this story at Schizophrenia Research Forum.
Like this: