Schizophrenia Research Forum

Cancer drugs help mouse model of schizophrenia

Experimental cancer drugs called PAK inhibitors can promote connections between neurons in a genetic mouse model of psychiatric disorders, reports a study  in the Proceedings of the National Academy of Sciences. The researchers developed compounds that inhibit p21-activated kinases (PAKs), and these protected or restored dendritic spines — the knobby recipients of inputs from other neurons — in the mice, and rescued deficits similar to those seen in schizophrenia.

Read this story at Schizophrenia Research Forum.

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