MeCP2 loss ups signal strength

Neurons lacking MeCP2, the protein deficient in Rett syndrome, have stronger signals than controls do when measured amid the electrical activity used by neurons to communicate. The findings suggest that how signals are measured can affect studies of other autism-related mutations.

Read this article at SFARI.

Sleep deprivation, cAMP, and schizophrenia

sleeplessThe cognitive difficulties stemming from sleep deprivation may be reversible, according to a recent paper in Nature. Using a drug that boosts levels of cAMP, a key molecule in neurons, scientists repaired memory formation in sleep-deprived mice. A similar approach may be useful in schizophrenia, a disorder that is sometimes marked by sleep disturbances and cAMP deficiencies.

Read this article at Schizophrenia Research Forum.