Disorganized brain signals in a mouse model of schizophrenia
Mice carrying a multi-gene deletion associated with schizophrenia exhibit disrupted communication between regions of the brain involved in working memory.Continue Reading
Category: Schizophrenia Research Forum
Convergence zone: top schizophrenia candidates linked
A new study outlines a connection between one suspected culprit in schizophrenia, NRG1, and another called DISC1. Read this articleContinue Reading
What lies between: extracellular matrix and schizophrenia
When searching for clues to schizophrenia in the brain, it’s important to look in the seemingly open space between neuronsContinue Reading
Serotonin receptors reduced in first-episode schizophrenia
The frontal cortex in people with schizophrenia contains abnormally low levels of the 5HT2A type of serotonin receptor, according to aContinue Reading
LRRTM2: A new synaptic partner for neurexin
A synapse-promoting protein called LRRTM2 has been identified as a ligand for neurexin, a protein linked to schizophrenia, autism andContinue Reading
Meet Norbin
Researchers have identified the protein Norbin as a behind the scenes booster of metabotropic glutamate receptors. This suggests a potentialContinue Reading
Getting specific with a mouse model of schizophrenia
Removing a subset of NMDA receptors in mice early in development can disrupt neural circuits and behavior in ways thatContinue Reading
GABA unleashed (from the synapse)
In the grand spectacle of neuronal communication, there is a new player on the scene: neurogliaform cells. A new paperContinue Reading
Sleep deprivation, cAMP, and schizophrenia
The cognitive difficulties stemming from sleep deprivation may be reversible, according to a recent paper in Nature. Using a drugContinue Reading
Michele Solis 