Perturbed molecular pathways in autism
The brain displays consistent but abnormal patterns of gene expression in autism, according to a new study in Nature. TheContinue Reading
Category: Schizophrenia Research Forum
The DISC1 switch
Disrupted in schizophrenia 1 (DISC1), a major susceptibility factor for schizophrenia and other mental disorders, acts as a switch betweenContinue Reading
Petri dish insights into schizophrenia
Neurons have been successfully grown from stem cells derived from people with schizophrenia, according to a new study in Nature.Continue Reading
Synaptic jacks of all trades
Two recent papers explore the role of schizophrenia susceptibility factors neuregulin 1 and its receptor ErbB4 in brain development andContinue Reading
Advancing drug discovery for schizophrenia
Over 200 researchers gathered at the lofty, fortieth floor location of the New York Academy of Sciences on 10-11 March 2011Continue Reading
Hyperactive clues to depression
A recent report in Nature links hyperactive synapses in the lateral habenula to learned helplessness in rats — a modelContinue Reading
Unpacking reelin’s role in neuronal migration
While building a brain early in development, young neurons use several methods of transportation to reach their final destination. AContinue Reading
Manipulating love and hate in the brain
According to a report in Nature, researchers have precisely identified and controlled neurons that mediate aggression in mice, even though theContinue Reading
A brain wrought without omega-3
A diet deficient in omega-3 fatty acids interferes with normal brain function, according to a report in Nature Neuroscience. MiceContinue Reading
Beyond cortex
Two brain imaging studies of people with schizophrenia find abnormal activity in the amygdala and the midbrain — brain regionsContinue Reading
Post-synaptic parts list
Researchers have identified 1461 proteins in the human post-synaptic density, a multi-protein complex that helps neurons communicate with each other.Continue Reading
Odd coupling in depression
A physical interaction between two types of dopamine receptor appears enhanced in human depression, and interfering with this coupling hasContinue Reading
Michele Solis 